Novel oral anticoagulants in oral and maxillofacial surgery: a comparison with warfarin between 2012-2014

Nazia Din, Barrett Andrew, Kenneth Eaton

Abstract


The records of anticoagulated patients who attended a maxillofacial surgical unit between 2012 and 2014 were reviewed. Data on 319 procedures performed on 249 patients were retrieved. During this period only seven patients (2.8%) were taking novel anticoagulants (NOACs) compared with 242 (97.2%) on warfarin. The seven patients underwent 11 surgical procedures. None of the seven were seen in 2012, three were seen in January 2013, the remaining four in 2014. Twenty-four (7.5%) of the 319 episodes were followed by prolonged bleeding; all occurred in patients taking warfarin. The seven NOAC patients’ hospital notes contained no recorded documentation of renal function, specifically the creatinine clearance or estimated glomerular filtration rate. 

Keywords


Bleeding, New anticoagulants, Rivaroxaban, Warfarin, Surgery

Full Text:

PDF

References


Griffiths M, Scully C. New anticoagulants. Brit Dent J 2012;13: 96.

Breik O, Cheng A, Sambrook P, Goss A. Protocol in managing oral surgical patients taking dabigatran. Aust Dent J 2014; 59: 296–301.

Pradaxa. Prescribers guide 2015. Available at: http://products.boehringer-ingelheim.com/pradaxa/sites/default/files/Prescriber_guide.pdf (Accessed: 10 May 2016).

Nice.org.uk. (2016). Reversal of the anticoagulant effect of dabigatran: idarucizumab | key-points-from-the-evidence | Advice | NICE. [online]. Available at: https://www.nice.org.uk/advice/esnm73/chapter/key-points-from-the evidence [accessed 27/11/2016].

Green B, Mendes R, van der Valk R, Brennan P. Novel anticoagulants - an update on the latest developments and management for clinicians treating patients on these drugs. J Oral Pathol Med 2016; 45: 551-556.

Sime G. [Online] Available at: http://www.sigwales.org/wp-content/uploads/dental-management-of-patients-taking-anticoagulant-drugs-outside-a-general-hospital-setting.pdf [Accessed 13 May 2016].

Gonsalves WI, Pruthi RK, Patnaik MM. The new oral anticoagulants in clinical practice. Mayo Clin Proc 2013; 88: 495–511.

Scottish Dental Clinical Effectiveness Programme. [Online] Management of dental patients taking anticoagulants or antiplatelet drugs. Available at: http://www.sdcep.org.uk/wp-content/uploads/2015/09/SDCEP-Anticoagulants-Guidance.pdf (Accessed: 1st February 2016).

Elad S, Marshall J, Meyerowitz C, Connolly G. Novel anticoagulants: general overview and practical considerations for dental practitioners. Oral Diseases 2016; 22: 23–32.


Refbacks

  • There are currently no refbacks.


Copyright (c) 2017 Advanced Journal of Professional Practice